HALIRA™

ONCOLOGY THERAPEUTIC PROGRAM

A novel small molecule approach that
starves cancer cells by blocking the energy they need to grow.

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Unique Mechanism

Targets the bioenergetic vulnerability of cancer cells.

Energy Deprivation

Blocks ATP production, eliminating the energy cancer cells need to survive.

Selective Action

Designed to minimize impact on normal cells.

Better Future

Advancing a new class of cancer therapeutics for companion animals.

HOW HALIRA™ WORKS

Starve the Cancer.
Stop the Growth.

Halira™ is a small molecule compound that penetrates cancer cells and disrupts the coupling of the electron transport chain (ETC) and ATP synthase, leading to a severe drop in ATP production. Without energy, cancer cells cannot grow, replicate, or survive.

Normal Cellular Energy Production

Nutrients → Electron Transport Chain (ETC) → ATP Synthase → ATP
(energy)
→ Cell Growth
& Survival

With Halira™

Nutrients → ETC✕ → ATP Synthase✕ → ATP
(energy)
→ No Energy
Cell Death
Halira™ small molecule ✕Inhibition

SCIENTIFIC RATIONALE

Targeting Cancer's Achilles' Heel: Energy Dependence

Cancer cells have extremely high energy demands to sustain rapid growth and replication. By shutting down ATP production, Halira™ exploits this dependency and induces metabolic collapse—leading to tumor cell death.

High Energy Demand

Cancer cells consume far more ATP than normal cells.

Metabolic Vulnerability

Blocking ATP production is a powerful strategy to kill cancer cells.

Therapeutic Advantage

Potential for broad application across various cancer types.

How HALIRA™ Works

HALIRA mechanism of action in five steps: oral administration, conversion into small molecules, blocking the electron transport chain and ATP synthase in cancer cells, relieving discomfort, and extending life

RESEARCH & DEVELOPMENT STATUS

  1. Discovery
  2. In Vitro Studies
  3. Preclinical Studies
  4. IND-Enabling
  5. Clinical Development

Halira™ is currently in preclinical development with robust in vitro and in vivo data demonstrating potent anti-tumor activity and a favorable safety profile.

IN VITRO & IN VIVO RESULTS

  • Potent inhibition of cancer cell proliferation
  • Significant reduction in ATP levels
  • Induction of cancer cell death
  • Favorable safety and tolerability profile

THE FUTURE OF ONCOLOGY CARE
FOR COMPANION ANIMALS

Halira™ represents a new class of energy-targeting therapeutics. Our mission is to bring innovative, effective, and safe cancer treatments to our beloved companion animals, improving both quality and length of life.

LEARN MORE ABOUT HALIRA™

Explore our science and stay updated on our progress.

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Halira™ is an investigational product and is not approved for any clinical use.
This information is intended for research collaboration and scientific exchange only.